Lutein and zeaxanthin are carotenoidsantioxidants made by plantsthat are believed to neutralize light-induced damage in the eye. Humans dont make carotenoids, so they can only be added to the body by eating plants or taking supplements. When we looked at the patients carotenoid levels in serum, skin, and the retina, all measurements were at least two times greater than carotenoid levels in patients not taking nutritional supplements, said Bernstein. The patient quit taking the lutein supplement, but maintained her diet rich in lutein, and, after seven months, the crystals in the right eye disappeared. While AREDS2 supplements are recommended to patients at higher risk for AMD, there has also been increased use in the general population. Bernsteins advice for his patients is that everyone should eat an eye-healthy diet rich in colorful fruits and vegetables, and individuals should take an AREDS2 supplement if their ophthalmologist detects signs of AMD. This case report must followed up by a larger clinical trial before the results can be considered conclusive but it serves as an indicator that there may be negative effects from consuming lutein considerably higher than the recommended AREDS2 dose. eye surgeonCitation: Rene Y. Choi, Susan C. Chortkoff, Aruna Gorusupudi, and Paul S. Bernstein. Crystalline Maculopathy Associated with High-Dose Lutein Supplementation.
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